James Carthew

James obtained his PhD from the University of Durham in 2016 which focused on exploring the roles of the LINC complex network in breast cancer metastasis and mechano-transduction. His PhD provided an insight into the roles of Nesprins in cellular migration and provided a proof of concept that nuclear deformability constitutes a rate limiting step in cellular migration through 3D culture environments, which could provide a novel target for cancer therapies in the near future.

In 2016, he joined the Frith lab at Monash University to explore the roles of target miRNAs and environmental influence on stem cell differentiation. His research interests cover the area of LINC complex derived mechano-transduction, mesenchymal stem cells, cancer metastasis, the cytoskeleton, extracellular matrix, materials engineering and tissue engineering.